Le SIDA au Ghana (serveur d'exploration)

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Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in sub-Saharan Africa: a randomised, double-blind, placebo-controlled trial.

Identifieur interne : 000937 ( Main/Exploration ); précédent : 000936; suivant : 000938

Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in sub-Saharan Africa: a randomised, double-blind, placebo-controlled trial.

Auteurs : George E. Armah [Ghana] ; Samba O. Sow ; Robert F. Breiman ; Michael J. Dallas ; Milagritos D. Tapia ; Daniel R. Feikin ; Fred N. Binka ; A Duncan Steele ; Kayla F. Laserson ; Nana A. Ansah ; Myron M. Levine ; Kristen Lewis ; Michele L. Coia ; Margaret Attah-Poku ; Joel Ojwando ; Stephen B. Rivers ; John C. Victor ; Geoffrey Nyambane ; Abraham Hodgson ; Florian Schödel ; Max Ciarlet ; Kathleen M. Neuzil

Source :

RBID : pubmed:20692030

Descripteurs français

English descriptors

Abstract

Rotavirus gastroenteritis causes many deaths in infants in sub-Saharan Africa. Because rotavirus vaccines have proven effective in developed countries but had not been tested in developing countries, we assessed efficacy of a pentavalent rotavirus vaccine against severe disease in Ghana, Kenya, and Mali between April, 2007, and March, 2009.

DOI: 10.1016/S0140-6736(10)60889-6
PubMed: 20692030


Affiliations:


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Le document en format XML

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<term>Administration, Oral</term>
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<term>Developing Countries</term>
<term>Double-Blind Method</term>
<term>Gastroenteritis (prevention & control)</term>
<term>Gastroenteritis (virology)</term>
<term>Humans</term>
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<term>Immunoglobulin A (blood)</term>
<term>Infant</term>
<term>Rotavirus (immunology)</term>
<term>Rotavirus Infections (immunology)</term>
<term>Rotavirus Infections (prevention & control)</term>
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<term>Rotavirus Vaccines (immunology)</term>
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<term>Infections à rotavirus</term>
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<term>Vaccins anti-rotavirus</term>
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<term>Rotavirus</term>
<term>Rotavirus Infections</term>
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<term>Gastroenteritis</term>
<term>Rotavirus Infections</term>
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<div type="abstract" xml:lang="en">Rotavirus gastroenteritis causes many deaths in infants in sub-Saharan Africa. Because rotavirus vaccines have proven effective in developed countries but had not been tested in developing countries, we assessed efficacy of a pentavalent rotavirus vaccine against severe disease in Ghana, Kenya, and Mali between April, 2007, and March, 2009.</div>
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